Trimethoprim-sulfamethoxazole can sharply raise INR in people taking warfarin, increasing bleeding risk. Learn why this happens, how to prevent it, and what to do if your INR spikes.
Dofetilide and cimetidine together can cause life-threatening heart rhythms. This interaction increases QT prolongation risk by up to 4 times, leading to torsades de pointes. Learn why this combo is strictly contraindicated and what to use instead.
Does vitamin D help you tolerate statins? Research shows mixed results. While some patients benefit, large trials find no overall effect. Learn who might still help and what to do if statins cause muscle pain.
Most people confuse side effects with true drug allergies. Learn how to tell the difference-why it matters, what symptoms to watch for, and how to get tested. Your next prescription could depend on it.
Fluoroquinolones and macrolides can cause dangerous QT prolongation, leading to life-threatening arrhythmias. Learn how to monitor ECGs, recognize high-risk patients, and choose safer alternatives to prevent cardiac events.
Learn how to spot dangerous drug combinations that raise overdose risk, including opioids with alcohol, benzodiazepines, and street drugs. Discover practical steps to check interactions, use naloxone, and talk to providers safely.
Aged cheeses and processed meats contain tyramine, which can cause life-threatening blood pressure spikes when taken with MAOI antidepressants. Learn which foods to avoid, safe alternatives, and how to prevent dangerous interactions.
Switching between brand-name and generic phenytoin can be risky due to its narrow therapeutic index and non-linear metabolism. Learn when and how to monitor levels to prevent seizures or toxicity.
Managing multiple medications safely means knowing which drugs are still necessary, spotting dangerous interactions, and working with your team to deprescribe when needed. Learn how to reduce risks and stay in control.
Antiretroviral HIV medications suppress the virus but face challenges from drug resistance and interactions. Learn how modern regimens work, why adherence matters, and what new treatments are changing the game.
Generic medications work just like brand-name drugs, but patient perceptions can trigger real side effects due to the nocebo effect. Learn how expectations, packaging, and communication shape treatment outcomes-and what you can do about it.
Learn how to safely split or crush pills without risking contamination, wrong doses, or exposure to hazardous drugs. Follow proven steps, use the right tools, and know which pills should never be broken.