Tag: narrow therapeutic index
10
Jan
Phenytoin and Generics: What You Need to Know About Therapeutic Drug Monitoring
Switching between brand-name and generic phenytoin can be risky due to its narrow therapeutic index and non-linear metabolism. Learn when and how to monitor levels to prevent seizures or toxicity.
4
Dec
Why Generic Switching Raises Concerns for NTI Drugs
Generic switching for NTI drugs like warfarin and phenytoin can cause dangerous fluctuations in blood levels, leading to toxicity or treatment failure. Learn why even small differences matter-and what patients and doctors must do to stay safe.