Narrow therapeutic index drugs require extreme precision in dosing. Learn what they are, which common medications fall into this category, why generic switches can be risky, and how to stay safe with regular monitoring and consistent sources.
Switching between brand-name and generic phenytoin can be risky due to its narrow therapeutic index and non-linear metabolism. Learn when and how to monitor levels to prevent seizures or toxicity.
Generic switching for NTI drugs like warfarin and phenytoin can cause dangerous fluctuations in blood levels, leading to toxicity or treatment failure. Learn why even small differences matter-and what patients and doctors must do to stay safe.