Tag: antiarrhythmic drug interaction

Dofetilide and Cimetidine: Why This Drug Pair Can Trigger Deadly Heart Rhythms
17
Jan
Dofetilide and Cimetidine: Why This Drug Pair Can Trigger Deadly Heart Rhythms
Medications 0 Comments

Dofetilide and cimetidine together can cause life-threatening heart rhythms. This interaction increases QT prolongation risk by up to 4 times, leading to torsades de pointes. Learn why this combo is strictly contraindicated and what to use instead.