Sinequan: What It Is, How to Use It, and What to Expect

If you’ve been handed a prescription for Sinequan, you might wonder what the drug actually does. Sinequan is the brand name for doxepin, a tricyclic antidepressant that also works as a powerful anti‑itch medication. Doctors prescribe it for depression, anxiety, and chronic skin itching that hasn’t responded to other treatments.

Typical Dosage and How to Take It

Most adults start with 25 mg once a day, usually at bedtime to help with sleep. Your doctor may raise the dose to 75 mg or more based on how you feel. For itching, doses can be lower—often 10 mg at night. Always follow the label: swallow the tablet whole, don’t crush or chew it, and try to take it at the same time each day.

If you miss a dose, take it as soon as you remember—unless it’s almost time for your next dose. In that case, skip the missed one and continue with your regular schedule. Never double‑up; too much doxepin can cause dizziness, rapid heartbeat, or blurry vision.

Common Side Effects and Safety Tips

Like many antidepressants, Sinequan can make you feel drowsy, dry‑mouthed, or a bit constipated. Some people get weight gain or a slight increase in appetite. Serious but rare reactions include fast heart rhythm, severe low blood pressure when you stand up, or confusion.

To stay safe, avoid alcohol while on Sinequan—it can boost drowsiness and raise the risk of falls. If you’re taking other meds, especially antihistamines, blood thinners, or other antidepressants, check with your pharmacist for possible interactions. Pregnant or nursing moms should talk to their doctor before starting.

When you first begin Sinequan, give your body a week or two to adjust. If side effects linger or feel harsh, let your doctor know. Sometimes a tiny dosage tweak can make a big difference.

Where to Buy Sinequan Legally

In most places, Sinequan is only available with a valid prescription. Ordering from a reputable online pharmacy that requires a doctor’s note protects you from counterfeit pills. Look for sites that display a licensed pharmacist, offer secure payment options, and have clear privacy policies.

Beware of “cheap Sinequan” ads that promise delivery without a prescription. Those often sell fake or unsafe drugs. If you need a refill, your best bet is to use your regular pharmacy’s mail‑order service or a trusted Canadian/US online pharmacy that follows local regulations.

Keeping a small stash of pills handy can help you stay on schedule, especially if you travel. Just make sure the bottle is labeled with the dosage and expiration date, and store it in a cool, dry place.

Bottom line: Sinequan can be a solid tool for lifting mood or calming stubborn itch, but it works best when you take it exactly as directed, watch for side effects, and source it from a legitimate pharmacy. Have questions? Your doctor or pharmacist is the right person to clear them up.